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Inosinate nucleosidase

From Wikipedia, the free encyclopedia
inosinate nucleosidase
Identifiers
EC no.3.2.2.12
CAS no.37288-61-2
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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PMCarticles
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NCBIproteins

In enzymology, an inosinate nucleosidase (EC 3.2.2.12) is an enzyme that catalyzes the chemical reaction

5'-inosinate + H2O D-ribose 5-phosphate + hypoxanthine

Thus, the two substrates of this enzyme are 5'-inosinate and H2O, whereas its two products are D-ribose 5-phosphate and hypoxanthine.

This enzyme belongs to the family of hydrolases, specifically those glycosylases that hydrolyse N-glycosyl compounds. The systematic name of this enzyme class is 5'-inosinate phosphoribohydrolase. This enzyme participates in purine metabolism.

References

[edit]
  • Kuninaka A (1957). "5'-Inosinic acid-N-ribosidase in Aspergillus". Koso Kagaka Shinojiumu. 12: 65–69.